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HDAC inhibitors improve CRISPR-Cas9 mediated prime editing and base editing
Recent advances in CRISPR-Cas9 techniques, especially the discovery of base and prime editing, have significantly improved our ability to make precise changes in the genome. We hypothesized that modulating certain endogenous pathway cells could improve the action of those editing tools in mammalian...
Autores principales: | Liu, Nan, Zhou, Lifang, Lin, Guifeng, Hu, Yun, Jiao, Yaoge, Wang, Yanhong, Liu, Jingming, Yang, Shengyong, Yao, Shaohua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9207553/ https://www.ncbi.nlm.nih.gov/pubmed/35784015 http://dx.doi.org/10.1016/j.omtn.2022.05.036 |
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