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Inferring disease progression and gene regulatory networks from clinical transcriptomic data using PROB_R
Due to a lack of explicit temporal information, it can be challenging to infer gene regulatory networks from clinical transcriptomic data. Here, we describe the protocol of PROB_R for inferring latent temporal disease progression and reconstructing gene regulatory networks from cross-sectional clini...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9207570/ https://www.ncbi.nlm.nih.gov/pubmed/35733604 http://dx.doi.org/10.1016/j.xpro.2022.101467 |