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Inferring disease progression and gene regulatory networks from clinical transcriptomic data using PROB_R

Due to a lack of explicit temporal information, it can be challenging to infer gene regulatory networks from clinical transcriptomic data. Here, we describe the protocol of PROB_R for inferring latent temporal disease progression and reconstructing gene regulatory networks from cross-sectional clini...

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Detalles Bibliográficos
Autores principales: Dong, Zhaorui, Sun, Xiaoqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9207570/
https://www.ncbi.nlm.nih.gov/pubmed/35733604
http://dx.doi.org/10.1016/j.xpro.2022.101467