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Halogenated bisphenol a analogues induce PPARγ-independent toxicity within human hepatocellular carcinoma cells

Tetrabromobisphenol A (TBBPA) and tetrachlorobisphenol A (TCBPA) – both halogenated bisphenol (BPA) analogues – are suspected ligands of peroxisome proliferator-activated receptor gamma (PPARγ). While previous studies have shown that TBBPA and TCBPA activate PPARγ within cell-free assays, the downst...

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Detalles Bibliográficos
Autores principales: Cheng, Vanessa, Volz, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9207610/
https://www.ncbi.nlm.nih.gov/pubmed/35734227
http://dx.doi.org/10.1016/j.crtox.2022.100079