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What the protein data bank tells us about the evolutionary conservation of protein conformational diversity

Proteins sample a multitude of different conformations by undergoing small‐ and large‐scale conformational changes that are often intrinsic to their functions. Information about these changes is often captured in the Protein Data Bank by the apparently redundant deposition of independent structural...

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Detalles Bibliográficos
Autores principales: Iyer, Mallika, Jaroszewski, Lukasz, Sedova, Mayya, Godzik, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9207624/
https://www.ncbi.nlm.nih.gov/pubmed/35762711
http://dx.doi.org/10.1002/pro.4325