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mRNA and tRNA modification states influence ribosome speed and frame maintenance during poly(lysine) peptide synthesis
Ribosome speed is dictated by multiple factors including substrate availability, cellular conditions, and product (peptide) formation. Translation slows during the synthesis of cationic peptide sequences, potentially influencing the expression of thousands of proteins. Available evidence suggests th...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9207662/ https://www.ncbi.nlm.nih.gov/pubmed/35595100 http://dx.doi.org/10.1016/j.jbc.2022.102039 |