Translation initiation factor eIF3a regulates glucose metabolism and cell proliferation via promoting small GTPase Rheb synthesis and AMPK activation

Eukaryotic translation initiation factor 3 subunit A (eIF3a), the largest subunit of the eIF3 complex, has been shown to be overexpressed in malignant cancer cells, potentially making it a proto-oncogene. eIF3a overexpression can drive cancer cell proliferation but contributes to better prognosis. W...

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Detalles Bibliográficos
Autores principales: Ma, Shijie, Dong, Zizheng, Huang, Yanfei, Liu, Jing-Yuan, Zhang, Jian-Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9207673/
https://www.ncbi.nlm.nih.gov/pubmed/35595099
http://dx.doi.org/10.1016/j.jbc.2022.102044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9207673/
https://www.ncbi.nlm.nih.gov/pubmed/35595099
http://dx.doi.org/10.1016/j.jbc.2022.102044

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