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Multiplexed quantification of insulin and C-peptide by LC-MS/MS without the use of antibodies

INTRODUCTION: The measurement of insulin and C-peptide provides a valuable tool for the clinical evaluation of hypoglycemia. In research, these biomarkers are used together to better understand hyperinsulinemia, hepatic insulin clearance, and beta cell function. Liquid chromatography-tandem mass spe...

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Detalles Bibliográficos
Autores principales: Foulon, North, Goonatilleke, Elisha, MacCoss, Michael J., Emrick, Michelle A., Hoofnagle, Andrew N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9207678/
https://www.ncbi.nlm.nih.gov/pubmed/35734440
http://dx.doi.org/10.1016/j.jmsacl.2022.06.003