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Mincle-binding DNA aptamer demonstrates therapeutic potential in a model of inflammatory bowel disease

Pattern recognition receptors such as Mincle (Clec4e) play a significant role in the regulation of inflammation. Enhanced signaling of Mincle through the release of damage-associated molecular patterns during sterile inflammation has been shown to be important in the progression and manifestation of...

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Detalles Bibliográficos
Autores principales: Stephens, Matthew, Keane, Keith, Roizes, Simon, Liao, Shan, Weid, Pierre-Yves von der
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9207717/
https://www.ncbi.nlm.nih.gov/pubmed/35782912
http://dx.doi.org/10.1016/j.omtn.2022.05.026