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Mincle-binding DNA aptamer demonstrates therapeutic potential in a model of inflammatory bowel disease
Pattern recognition receptors such as Mincle (Clec4e) play a significant role in the regulation of inflammation. Enhanced signaling of Mincle through the release of damage-associated molecular patterns during sterile inflammation has been shown to be important in the progression and manifestation of...
Autores principales: | Stephens, Matthew, Keane, Keith, Roizes, Simon, Liao, Shan, Weid, Pierre-Yves von der |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9207717/ https://www.ncbi.nlm.nih.gov/pubmed/35782912 http://dx.doi.org/10.1016/j.omtn.2022.05.026 |
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