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Tumour-draining lymph nodes in head and neck cancer are characterized by accumulation of CTLA-4 and PD-1 expressing Treg cells

INTRODUCTION: High Tregs infiltration within the tumour microenvironment (TME) of various cancers shows a positive correlation with poor prognosis. Despite the fact that tumour draining lymph nodes (TDLNs) are recognized as key organs playing a crucial role in response to immunotherapy and modulatin...

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Detalles Bibliográficos
Autores principales: Piersiala, Krzysztof, da Silva, Pedro Farrajota Neves, Lagebro, Vilma, Kolev, Aeneas, Starkhammar, Magnus, Elliot, Alexandra, Marklund, Linda, Munck-Wikland, Eva, Margolin, Gregori, Georén, Susanna Kumlien, Cardell, Lars-Olaf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9207719/
https://www.ncbi.nlm.nih.gov/pubmed/35714487
http://dx.doi.org/10.1016/j.tranon.2022.101469