Fluorescence-Based Activity Screening Assay Reveals Small Molecule Inhibitors of Vaccinia Virus mRNA Decapping Enzyme D9

[Image: see text] Vaccinia virus (VACV) represents a family of poxviruses, which possess their own decapping machinery as a part of their strategy to eliminate host mRNAs and evade the innate immune response. D9 is one of the two encoded VACV decapping enzymes that is responsible for cap removal fro...

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Detalles Bibliográficos
Autores principales: Bednarczyk, Marcelina, Peters, Jessica K., Kasprzyk, Renata, Starek, Jagoda, Warminski, Marcin, Spiewla, Tomasz, Mugridge, Jeffrey S., Gross, John D., Jemielity, Jacek, Kowalska, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9207806/
https://www.ncbi.nlm.nih.gov/pubmed/35576528
http://dx.doi.org/10.1021/acschembio.2c00049

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9207806/
https://www.ncbi.nlm.nih.gov/pubmed/35576528
http://dx.doi.org/10.1021/acschembio.2c00049

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