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Characterization of the Key Determinants of Phd Antitoxin Mediated Doc Toxin Inactivation in Salmonella

[Image: see text] In the search for novel antimicrobial therapeutics, toxin-antitoxin (TA) modules are promising yet underexplored targets for overcoming antibiotic failure. The bacterial toxin Doc has been associated with the persistence of Salmonella in macrophages, enabling its survival upon anti...

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Detalles Bibliográficos
Autores principales: de Castro, Guilherme V., Worm, Dennis J., Grabe, Grzegorz J., Rowan, Fiona C., Haggerty, Lucy, de la Lastra, Ana L., Popescu, Oana, Helaine, Sophie, Barnard, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9207808/
https://www.ncbi.nlm.nih.gov/pubmed/35647667
http://dx.doi.org/10.1021/acschembio.2c00276