Cargando…
Characterization of the Key Determinants of Phd Antitoxin Mediated Doc Toxin Inactivation in Salmonella
[Image: see text] In the search for novel antimicrobial therapeutics, toxin-antitoxin (TA) modules are promising yet underexplored targets for overcoming antibiotic failure. The bacterial toxin Doc has been associated with the persistence of Salmonella in macrophages, enabling its survival upon anti...
Autores principales: | de Castro, Guilherme V., Worm, Dennis J., Grabe, Grzegorz J., Rowan, Fiona C., Haggerty, Lucy, de la Lastra, Ana L., Popescu, Oana, Helaine, Sophie, Barnard, Anna |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9207808/ https://www.ncbi.nlm.nih.gov/pubmed/35647667 http://dx.doi.org/10.1021/acschembio.2c00276 |
Ejemplares similares
-
Functional validation of putative toxin-antitoxin genes from the Gram-positive pathogen Streptococcus pneumoniae: phd-doc is the fourth bona-fide operon
por: Chan, Wai Ting, et al.
Publicado: (2014) -
Doc toxin is a kinase that inactivates elongation factor Tu.
por: Cruz, Jonathan W., et al.
Publicado: (2014) -
A Toxin-Antitoxin Module of Salmonella Promotes Virulence in Mice
por: De la Cruz, Miguel A., et al.
Publicado: (2013) -
Activity of acetyltransferase toxins involved in Salmonella persister formation during macrophage infection
por: Rycroft, Julian A., et al.
Publicado: (2018) -
Diverse distribution of Toxin-Antitoxin II systems in Salmonella enterica serovars
por: Di Cesare, Andrea, et al.
Publicado: (2016)