Targeting cyclin-dependent kinase 1 (CDK1) in cancer: molecular docking and dynamic simulations of potential CDK1 inhibitors

Cell cycle dysregulation is a characteristic hallmark of malignancies, which results in uncontrolled cell proliferation and eventual tumor formation. Cyclin-dependent kinase 1 (CDK1) is a member of the family of cell cycle regulatory proteins involved in cell cycle maintenance. Given that overexpres...

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Detalles Bibliográficos
Autores principales: Sofi, Shazia, Mehraj, Umar, Qayoom, Hina, Aisha, Shariqa, Almilaibary, Abdullah, Alkhanani, Mustfa, Mir, Manzoor Ahmad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9207877/
https://www.ncbi.nlm.nih.gov/pubmed/35723742
http://dx.doi.org/10.1007/s12032-022-01748-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9207877/
https://www.ncbi.nlm.nih.gov/pubmed/35723742
http://dx.doi.org/10.1007/s12032-022-01748-2

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