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A Biocatalytic Platform for the Synthesis of Enantiopure Propargylic Alcohols and Amines

[Image: see text] Propargylic alcohols and amines are versatile building blocks in organic synthesis. We demonstrate a straightforward enzymatic cascade to synthesize enantiomerically pure propargylic alcohols and amines from readily available racemic starting materials. In the first step, the perox...

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Detalles Bibliográficos
Autores principales: Sang, Xianke, Tong, Feifei, Zeng, Zhigang, Wu, Minghu, Yuan, Bo, Sun, Zhoutong, Sheng, Xiang, Qu, Ge, Alcalde, Miguel, Hollmann, Frank, Zhang, Wuyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9208015/
https://www.ncbi.nlm.nih.gov/pubmed/35670732
http://dx.doi.org/10.1021/acs.orglett.2c01547