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E‐cadherin is a robust prognostic biomarker in colorectal cancer and low expression is associated with sensitivity to inhibitors of topoisomerase, aurora, and HSP90 in preclinical models

Cell–cell and cell–matrix adhesion proteins that have been implicated in colorectal epithelial integrity and epithelial‐to‐mesenchymal transition could be robust prognostic and potential predictive biomarkers for standard and novel therapies. We analyzed in situ protein expression of E‐cadherin (ECA...

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Detalles Bibliográficos
Autores principales: Bruun, Jarle, Eide, Peter W., Bergsland, Christian Holst, Bruck, Oscar, Svindland, Aud, Arjama, Mariliina, Välimäki, Katja, Bjørnslett, Merete, Guren, Marianne G., Kallioniemi, Olli, Nesbakken, Arild, Lothe, Ragnhild A., Pellinen, Teijo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9208074/
https://www.ncbi.nlm.nih.gov/pubmed/34890102
http://dx.doi.org/10.1002/1878-0261.13159