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E‐cadherin is a robust prognostic biomarker in colorectal cancer and low expression is associated with sensitivity to inhibitors of topoisomerase, aurora, and HSP90 in preclinical models
Cell–cell and cell–matrix adhesion proteins that have been implicated in colorectal epithelial integrity and epithelial‐to‐mesenchymal transition could be robust prognostic and potential predictive biomarkers for standard and novel therapies. We analyzed in situ protein expression of E‐cadherin (ECA...
Autores principales: | Bruun, Jarle, Eide, Peter W., Bergsland, Christian Holst, Bruck, Oscar, Svindland, Aud, Arjama, Mariliina, Välimäki, Katja, Bjørnslett, Merete, Guren, Marianne G., Kallioniemi, Olli, Nesbakken, Arild, Lothe, Ragnhild A., Pellinen, Teijo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9208074/ https://www.ncbi.nlm.nih.gov/pubmed/34890102 http://dx.doi.org/10.1002/1878-0261.13159 |
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