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Blockade of the Arid5a/IL-6/STAT3 axis underlies the anti-inflammatory effect of Rbpjl in acute pancreatitis

BACKGROUND: The microarray data analysis predicted that Rbpjl is poorly expressed in acute pancreatitis (AP). Activated IL-6/STAT3 signaling is further known to contribute to the progression of AP through immune regulation, and both IL-6 and STAT3 were bioinformatically predicted to interact with Ar...

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Detalles Bibliográficos
Autores principales: Lv, Jiachen, Fang, Min, Sun, Shijie, Wang, Gang, Fu, Songbin, Sun, Bei, Tong, Jinxue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9208186/
https://www.ncbi.nlm.nih.gov/pubmed/35725649
http://dx.doi.org/10.1186/s13578-022-00819-1