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Metabolomics and integrated network pharmacology analysis reveal SNKAF decoction suppresses cell proliferation and induced cell apoptisis in hepatocellular carcinoma via PI3K/Akt/P53/FoxO signaling axis

BACKGROUND: There is no comprehensive treatment method for hepatocellular carcinoma (HCC); hence, research and development are still focused on systemic therapies, including drugs. Sinikangai fang (SNKAF) decoction, a classic Chinese herbal prescription, has been widely used to treat liver cancer. H...

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Detalles Bibliográficos
Autores principales: Guo, Wei, Yao, Xiaohui, Lan, Siyuan, Zhang, Chi, Li, Hanhan, Chen, Zhuangzhong, Yu, Ling, Liu, Guanxian, Lin, Yuan, Liu, Shan, Chen, Hanrui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9208213/
https://www.ncbi.nlm.nih.gov/pubmed/35725485
http://dx.doi.org/10.1186/s13020-022-00628-1