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Contribution and clinical relevance of germline variation to the cancer transcriptome

BACKGROUND: Somatic alterations in the cancer genome, some of which are associated with changes in gene expression, have been characterized in multiple studies across diverse cancer types. However, less is known about germline variants that influence tumor biology by shaping the cancer transcriptome...

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Detalles Bibliográficos
Autores principales: Pereira, Bernard, Labrot, Emma, Durand, Eric, Korn, Joshua M., Kauffmann, Audrey, Campbell, Catarina D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9208227/
https://www.ncbi.nlm.nih.gov/pubmed/35725412
http://dx.doi.org/10.1186/s12885-022-09757-0