Novel Diagnostic and Therapeutic Options for KMT2A-Rearranged Acute Leukemias

The KMT2A (MLL) gene rearrangements (KMT2A-r) are associated with a diverse spectrum of acute leukemias. Although most KMT2A-r are restricted to nine partner genes, we have recently revealed that KMT2A-USP2 fusions are often missed during FISH screening of these genetic alterations. Therefore, compl...

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Detalles Bibliográficos
Autores principales: Lopes, Bruno A., Poubel, Caroline Pires, Teixeira, Cristiane Esteves, Caye-Eude, Aurélie, Cavé, Hélène, Meyer, Claus, Marschalek, Rolf, Boroni, Mariana, Emerenciano, Mariana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9208280/
https://www.ncbi.nlm.nih.gov/pubmed/35734412
http://dx.doi.org/10.3389/fphar.2022.749472

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9208280/
https://www.ncbi.nlm.nih.gov/pubmed/35734412
http://dx.doi.org/10.3389/fphar.2022.749472

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