Increased homocysteine regulated by androgen activates autophagy by suppressing the mammalian target of rapamycin pathway in the granulosa cells of polycystic ovary syndrome mice

The purpose of this study was to explore the potential molecular mechanisms of excess homocysteine in relation to autophagic activity in the ovarian tissue of polycystic ovarian syndrome (PCOS) with hyperandrogenism.A PCOS model was constructed using ICR mice. ELISA was used to detect the Hcy levels...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Ting, Dong, Guogang, Kang, Yani, Zhang, Mei, Sheng, Xiaoqiang, Wang, Zhilong, Liu, Yang, Kong, Na, Sun, Haixiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9208444/
https://www.ncbi.nlm.nih.gov/pubmed/35485387
http://dx.doi.org/10.1080/21655979.2022.2066608

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9208444/
https://www.ncbi.nlm.nih.gov/pubmed/35485387
http://dx.doi.org/10.1080/21655979.2022.2066608

Ejemplares similares