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Clemastine protects against sepsis-induced myocardial injury in vivo and in vitro

Sepsis-induced myocardial dysfunction (SIMD) is associated with high morbidity and mortality rates; however, it lacks targeted therapies. Modulating cardiomyocyte autophagy maintains intracellular homeostasis during SIMD. Clemastine, a histamine receptor inhibitor, promotes autophagy and other effec...

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Detalles Bibliográficos
Autores principales: Wang, Xiaowan, Xie, Di, Dai, Hui, Ye, Jiawei, Liu, Yuqi, Fei, Aihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9208445/
https://www.ncbi.nlm.nih.gov/pubmed/35274595
http://dx.doi.org/10.1080/21655979.2022.2047256