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Comparative Structural Analysis of Human ACE2 Receptor with Spike Protein of SARS-CoV-2 Variants: Implications to Understand Infectivity of the Virus

PURPOSE: Spike protein on SARS-CoV-2 virus plays an integral part during infection as cell entry depends on binding of this protein to human ACE2 receptor. Understanding of infectivity by these variants necessitates a comparative structural analysis of complexes of spike protein-receptor binding dom...

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Detalles Bibliográficos
Autores principales: Koley, Tirthankar, Goswami, Arunima, Kumar, Manoj, Upadhyay, Neelam, Hariprasad, Gururao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9208465/
https://www.ncbi.nlm.nih.gov/pubmed/35734581
http://dx.doi.org/10.2147/AABC.S360787