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MEK1/2 inhibitor inhibits neointima formation by activating miR-126-3p/ C-X-C motif chemokine ligand 12 (CXCL12)/C-X-C motif chemokine receptor 4 (CXCR4) axis

Endothelial dysfunction is an initial and essential step in vascular-remodeling diseases, including atherosclerosis and neointima formation. During vascular remodeling, activated endothelial cells can release pro-inflammatory factors that promote phenotypic switching of vascular smooth muscle cells...

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Detalles Bibliográficos
Autores principales: Yan, Yali, Zhu, Mengmeng, Ma, Jialing, He, Xiaoyu, Yang, Xiaoxiao, Xu, Hongmei, Jiang, Meixiu, Zhang, Shuang, Duan, Yajun, Han, Jihong, Chen, Yuanli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9208476/
https://www.ncbi.nlm.nih.gov/pubmed/35485167
http://dx.doi.org/10.1080/21655979.2022.2063496