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P53 and taurine upregulated gene 1 promotes the repair of the DeoxyriboNucleic Acid damage induced by bupivacaine in murine primary sensory neurons

The research aimed to explore the biological role of p53 protein and long non-coding RNA (lncRNA) taurine upregulated gene 1 (TUG1) in bupivacaine (bup)-induced neurotoxicity. Our work treated dorsal root ganglion (DRG) cells with bup, detected cell viability through CCK-8, apoptosis through TUNEL a...

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Detalles Bibliográficos
Autores principales: Lai, Luying, Wang, Yongwei, Peng, Shenghui, Guo, Wenjing, Li, Fengxian, Xu, Shiyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9208530/
https://www.ncbi.nlm.nih.gov/pubmed/35271399
http://dx.doi.org/10.1080/21655979.2022.2048985