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Origin and significance of the human DNase repertoire

The human genome contains four DNase1 and two DNase2 genes. The origin and functional specialization of this repertoire are not fully understood. Here we use genomics and transcriptomics data to infer the evolutionary history of DNases and investigate their biological significance. Both DNase1 and D...

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Detalles Bibliográficos
Autores principales: Mori, Giulia, Delfino, Danila, Pibiri, Paola, Rivetti, Claudio, Percudani, Riccardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9208542/
https://www.ncbi.nlm.nih.gov/pubmed/35725583
http://dx.doi.org/10.1038/s41598-022-14133-w