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The Level of Histone Deacetylase 4 is Associated with Aging Cartilage Degeneration and Chondrocyte Hypertrophy

PURPOSE: To determine the role of histone deacetylase 4 (HDAC4)-controlled chondrocyte hypertrophy in the onset and development of age-related osteoarthritis (OA). METHODS: Morphological analysis of human knee cartilages was performed to observe structural changes during cartilage degeneration. HDAC...

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Detalles Bibliográficos
Autores principales: Dong, Zhengquan, Ma, Zhou, Yang, Meiju, Cong, Linlin, Zhao, Ruipeng, Cheng, Liyun, Sun, Jian, Wang, Yunfei, Yang, Ruijia, Wei, Xiaochun, Li, Pengcui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9208673/
https://www.ncbi.nlm.nih.gov/pubmed/35734099
http://dx.doi.org/10.2147/JIR.S365545