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The Level of Histone Deacetylase 4 is Associated with Aging Cartilage Degeneration and Chondrocyte Hypertrophy
PURPOSE: To determine the role of histone deacetylase 4 (HDAC4)-controlled chondrocyte hypertrophy in the onset and development of age-related osteoarthritis (OA). METHODS: Morphological analysis of human knee cartilages was performed to observe structural changes during cartilage degeneration. HDAC...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9208673/ https://www.ncbi.nlm.nih.gov/pubmed/35734099 http://dx.doi.org/10.2147/JIR.S365545 |