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Ancestral reconstruction of duplicated signaling proteins reveals the evolution of signaling specificity

Gene duplication is crucial to generating novel signaling pathways during evolution. However, it remains unclear how the redundant proteins produced by gene duplication ultimately acquire new interaction specificities to establish insulated paralogous signaling pathways. Here, we used ancestral sequ...

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Detalles Bibliográficos
Autores principales: Nocedal, Isabel, Laub, Michael T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9208753/
https://www.ncbi.nlm.nih.gov/pubmed/35686729
http://dx.doi.org/10.7554/eLife.77346