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Ancestral reconstruction of duplicated signaling proteins reveals the evolution of signaling specificity
Gene duplication is crucial to generating novel signaling pathways during evolution. However, it remains unclear how the redundant proteins produced by gene duplication ultimately acquire new interaction specificities to establish insulated paralogous signaling pathways. Here, we used ancestral sequ...
Autores principales: | Nocedal, Isabel, Laub, Michael T |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9208753/ https://www.ncbi.nlm.nih.gov/pubmed/35686729 http://dx.doi.org/10.7554/eLife.77346 |
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