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B-cell Receptor Signaling Induced Metabolic Alterations in Chronic Lymphocytic Leukemia Can Be Partially Bypassed by TP53 Abnormalities

It has been unclear what role metabolism is playing in the pathophysiology of chronic lymphocytic leukemia (CLL). One reason is that the study of CLL metabolism is challenging due to the resting nature of circulating CLL cells. Also, it is not clear if any of the genomic aberrations observed in this...

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Detalles Bibliográficos
Autores principales: Kluckova, Katarina, Clear, Andrew J., D’Avola, Annalisa, Rassenti, Laura Z., Kipps, Thomas J., Gribben, John G., Riches, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9208879/
https://www.ncbi.nlm.nih.gov/pubmed/35747847
http://dx.doi.org/10.1097/HS9.0000000000000722