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405 Role of Glycans in Cancer Associated Fibroblast-Derived Exosome Immunoregulation

OBJECTIVES/GOALS: To identify the role of sialoglycans in the mechanisms underlying cancer-associated fibroblast-derived exosomes (CAFEX) immuno-regulatory properties. The central hypothesis is that CAFEX manipulates the immune response to allow immunoevasion and glycomic approaches can identify the...

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Detalles Bibliográficos
Autores principales: Anderson, Johnathon D., Nolta, Jan, Farwell, D. Gregory, Birkland, Andrew, Van de Water, Judy, Carraway, Kermit, Lebrilla, Carlito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9209014/
http://dx.doi.org/10.1017/cts.2022.233