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436 Examining the Role of Obesity and Leptin Signaling in Triple Negative Breast Cancer

OBJECTIVES/GOALS: In triple negative breast cancer (TNBC), obesity is associated with poor outcomes. Adipose stem cells (ASCs) from obese patients (obASCs) secrete higher levels of adipokines compared to ASCs from lean individuals. Leptin, one of these adipokines, has been implicated in many cancers...

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Detalles Bibliográficos
Autores principales: Brock, Courtney, Wright, Maryl K., Nguyen, Khoa, Hebert, Katherine, Alzoubi, Madlin, Cheng, Thomas, Collins-Burow, Bridgette M., Burow, Matthew E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9209033/
http://dx.doi.org/10.1017/cts.2022.254