440 Modulating decreases in Superior Colliculus activity through optogenetic activation attenuates seizures in the WAG/Rij genetic model of Absence Epilepsy

OBJECTIVES/GOALS: While anti-seizure medications are effective, nearly one third of patients have seizures that go untreated. Prior studies using evoked seizure models have shown that activation of the Superior Colliculus (SC) display anti-seizure effects. Here we monitored and modulated the DLSC to...

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Detalles Bibliográficos
Autores principales: Palmer, Devin D., Campos-Rodriquez, Carolina, Forcelli, Patrick A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2022
Materias:
Valued Approaches
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9209090/
http://dx.doi.org/10.1017/cts.2022.257

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9209090/
http://dx.doi.org/10.1017/cts.2022.257

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