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411 Essential role for the neurodevelopmental disorder-linked gene, MEF2C, in inhibitory neuron function and neurotypical behaviors

OBJECTIVES/GOALS: The MEF2 family of transcription factors regulate gene expression controlling cell differentiation and synapse development. Mutations or deletions in the MEF2C gene cause a neurodevelopmental disorder that includes symptoms of autism spectrum disorder. In this study, we aim to stud...

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Detalles Bibliográficos
Autores principales: Cho, Yongjoo (Jennifer), Assali, Ahlem, Tsvetkov, Evgeny, Cowan, Christopher W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9209091/
http://dx.doi.org/10.1017/cts.2022.238