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433 Is miR let-7c protective against Acute Chest Syndrome in Sickle Cell Disease?

OBJECTIVES/GOALS: We have shown that small extracellular vesicles (exosomes) isolated from patients with a history of ACS disrupt the endothelium in vitro. Sequencing of miRNA contents of these vesicles suggested that miR let-7c was differentially expressed. The current study was designed to determi...

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Detalles Bibliográficos
Autores principales: Fan, James, Gemel, Joanna, Lang, Theodore, Beyer, Eric, Lapping-Carr, Gabrielle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9209192/
http://dx.doi.org/10.1017/cts.2022.251