255 A Bacterial Serine Protease Inhibitor, Ecotin Inhibits Neutrophil Elastase in Cystic Fibrosis Airway Samples

OBJECTIVES/GOALS: Ecotin is a potent periplasmic serin protease inhibitor that was first described in Escherichia coli (E. coli). Ecotin is known to inhibit a broad range of serine proteases including NE. Therefore, we hypothesized that ecotin can inhibit the NE activity present in CF clinical sputu...

Descripción completa

Detalles Bibliográficos
Autores principales: Fantone, Kayla, Crippen, Clay, Nothaft, Harald, Stecenko, Arlene, Szymanski, Christine, Rada, Balazs
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2022
Materias:
Valued Approaches
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9209219/
http://dx.doi.org/10.1017/cts.2022.138

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9209219/
http://dx.doi.org/10.1017/cts.2022.138

Ejemplares similares