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462 Dysfunctional leukocyte mitochondrial metabolism is associated with immune paralysis in critically ill septic patients

OBJECTIVES/GOALS: The host immune response during sepsis is now recognized to have anti-inflammatory pathophysiology. We aim to determine whether mitochondrial dysfunction of leukocytes predicts which critically ill septic patients develop immune paralysis and to identify differences in cellular met...

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Detalles Bibliográficos
Autores principales: Torres, Lisa K, McConn, Keith, Gomez-Escobar, Luis, Cloonan, Suzanne, Choi, Augustine MK
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9209230/
http://dx.doi.org/10.1017/cts.2022.271