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462 Dysfunctional leukocyte mitochondrial metabolism is associated with immune paralysis in critically ill septic patients
OBJECTIVES/GOALS: The host immune response during sepsis is now recognized to have anti-inflammatory pathophysiology. We aim to determine whether mitochondrial dysfunction of leukocytes predicts which critically ill septic patients develop immune paralysis and to identify differences in cellular met...
Autores principales: | Torres, Lisa K, McConn, Keith, Gomez-Escobar, Luis, Cloonan, Suzanne, Choi, Augustine MK |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cambridge University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9209230/ http://dx.doi.org/10.1017/cts.2022.271 |
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