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329 Longitudinal immune profiling reveals unique myeloid and T cell phenotypes associated with spontaneous immunoediting in a novel prostate tumor model

OBJECTIVES/GOALS: Few preclinical models exist to study how tumors transition from prolonged stable disease ('equilibrium') to progressive disease ('escape'). We characterized a new murine tumor model the exhibits such behavior, and sought to identify and validate the role of uni...

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Detalles Bibliográficos
Autores principales: Ager, Casey, Obradovic, Aleksandar, Arriaga, Juan M., Chaimowitz, Matthew G., Abate-Shen, Cory, Califano, Andrea, Drake, Charles G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9209243/
http://dx.doi.org/10.1017/cts.2022.186