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302 Abaloparatide as a novel therapy for posttraumatic osteoarthritis
OBJECTIVES/GOALS: Osteoarthritis (OA) is a cartilage destroying disease. We are investigating abaloparatide (ABL) activation of parathyroid hormone receptor type 1 (PTH1R), which is expressed by articular chondrocytes in OA. We propose ABL treatment is chondroprotective in murine PTOA via stimulatio...
Autores principales: | Landgrave, Samantha H., Ishii, Toru, Maynard, Robert, Wu, Andrew, Godfrey, Dana, Manes, Terrin, Butler, Veronica, Villani, David, Hendesi, Honey, Frank, Rachel, Iyer, Srividhya, Payne, Karin, Adams, Douglas J., Favazzo, Lacey, Lanske, Beate, Zuscik, Michael J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cambridge University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9209282/ http://dx.doi.org/10.1017/cts.2022.166 |
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