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352 Computational methods for predicting drug combinations for targeting KRAS mutations relevant to non-small cell lung cancer

OBJECTIVES/GOALS: Our goal is to develop a cost-effective approach for precision medicine treatment by providing computational predictions for new uses of currently available FDA approved, and experimental drugs for NSCLC. METHODS/STUDY POPULATION: Cell Lines: A549 (ATCC- CCL-185) Human epithelial L...

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Detalles Bibliográficos
Autores principales: Bruggemann, Liana, Falls, Zackary, Mangione, William, Mahajan, Supriya, Samudrala, Ram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9209286/
http://dx.doi.org/10.1017/cts.2022.200