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410 Mild Maternal Undernutrition Results in a Premature Neonatal Leptin Surge and Resistance in Male Offspring to a High Fat Diet

OBJECTIVES/GOALS: Maternal undernutrition, a form of malnutrition, can alter neonatal leptin signaling and result in metabolic dysfunction in adulthood. We developed a mild undernutrition model to relate more to societys nutritional challenges and to test the hypothesis that a shift in the neonatal...

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Detalles Bibliográficos
Autores principales: Miles, Tiffany K., Allensworth, Melody L., Silva Moreira, Ana Rita, Odle, Angela K., Haney, Anessa, Lagasse, Alexandra, MacNicol, Angus M., Childs, Gwen V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9209293/
http://dx.doi.org/10.1017/cts.2022.237