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321 Impact of CDK4/6 inhibitor-induced cellular senescence on stromal responses to breast cancer

OBJECTIVES/GOALS: The objective of my study is to test my overall hypothesis that CDK4/6 inhibitor-induced cellular senescence has long-lasting consequences on the tumor microenvironment that affect tumor growth and disease progression. METHODS/STUDY POPULATION: There is a lack of mechanistic unders...

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Detalles Bibliográficos
Autores principales: Gallanis, Gregory T., Wellstein, Anton, Riegel, Anna T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9209308/
http://dx.doi.org/10.1017/cts.2022.179