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Highly sensitive and non-disruptive detection of residual undifferentiated cells by measuring miRNAs in culture supernatant

The clinical usage of induced pluripotent stem cell (iPSC)-derived regenerative medicine products is limited by the possibility of residual undifferentiated cells forming tumours after transplantation. Most of the existing quality control tests involve crushing of cells. As a result, the cells to be...

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Detalles Bibliográficos
Autores principales: Masumoto, Kanako, Aihara, Yuki, Miyagawa Kuroishi, Mao, Maeda, Natsuki, Sakai, Yumiko, Oka, Yuma, Takahashi, Yusuke, Oda, Kenta, Yanagida, Masatoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9209417/
https://www.ncbi.nlm.nih.gov/pubmed/35725891
http://dx.doi.org/10.1038/s41598-022-14273-z