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Highly sensitive and non-disruptive detection of residual undifferentiated cells by measuring miRNAs in culture supernatant
The clinical usage of induced pluripotent stem cell (iPSC)-derived regenerative medicine products is limited by the possibility of residual undifferentiated cells forming tumours after transplantation. Most of the existing quality control tests involve crushing of cells. As a result, the cells to be...
Autores principales: | Masumoto, Kanako, Aihara, Yuki, Miyagawa Kuroishi, Mao, Maeda, Natsuki, Sakai, Yumiko, Oka, Yuma, Takahashi, Yusuke, Oda, Kenta, Yanagida, Masatoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9209417/ https://www.ncbi.nlm.nih.gov/pubmed/35725891 http://dx.doi.org/10.1038/s41598-022-14273-z |
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