HarmonizR enables data harmonization across independent proteomic datasets with appropriate handling of missing values

Dataset integration is common practice to overcome limitations in statistically underpowered omics datasets. Proteome datasets display high technical variability and frequent missing values. Sophisticated strategies for batch effect reduction are lacking or rely on error-prone data imputation. Here...

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Detalles Bibliográficos
Autores principales: Voß, Hannah, Schlumbohm, Simon, Barwikowski, Philip, Wurlitzer, Marcus, Dottermusch, Matthias, Neumann, Philipp, Schlüter, Hartmut, Neumann, Julia E., Krisp, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9209422/
https://www.ncbi.nlm.nih.gov/pubmed/35725563
http://dx.doi.org/10.1038/s41467-022-31007-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9209422/
https://www.ncbi.nlm.nih.gov/pubmed/35725563
http://dx.doi.org/10.1038/s41467-022-31007-x

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