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Cognition as a mediator for gait and balance impairments in GBA-related Parkinson’s disease

The extent to which the heterogeneity of gait and balance problems in PD may be explained by genetic variation is unknown. Variants in the glucocerebrosidase (GBA) gene are the strongest known genetic risk factor for PD and are associated with greater motor and cognitive severity. However, the impac...

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Detalles Bibliográficos
Autores principales: Morris, Rosie, Martini, Douglas N., Ramsey, Katrina, Kelly, Valerie E., Smulders, Katrijn, Hiller, Amie, Chung, Kathryn A., Hu, Shu-Ching, Zabetian, Cyrus P., Poston, Kathleen L., Mata, Ignacio F., Edwards, Karen L., Lapidus, Jodi, Cholerton, Brenna, Montine, Thomas J., Quinn, Joseph F., Horak, Fay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9209443/
https://www.ncbi.nlm.nih.gov/pubmed/35725575
http://dx.doi.org/10.1038/s41531-022-00344-5