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Cognition as a mediator for gait and balance impairments in GBA-related Parkinson’s disease
The extent to which the heterogeneity of gait and balance problems in PD may be explained by genetic variation is unknown. Variants in the glucocerebrosidase (GBA) gene are the strongest known genetic risk factor for PD and are associated with greater motor and cognitive severity. However, the impac...
Autores principales: | Morris, Rosie, Martini, Douglas N., Ramsey, Katrina, Kelly, Valerie E., Smulders, Katrijn, Hiller, Amie, Chung, Kathryn A., Hu, Shu-Ching, Zabetian, Cyrus P., Poston, Kathleen L., Mata, Ignacio F., Edwards, Karen L., Lapidus, Jodi, Cholerton, Brenna, Montine, Thomas J., Quinn, Joseph F., Horak, Fay |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9209443/ https://www.ncbi.nlm.nih.gov/pubmed/35725575 http://dx.doi.org/10.1038/s41531-022-00344-5 |
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